This text accommodates paid for content material produced in collaboration with Arvia Know-how.

Lively Pharmaceutical Elements (APIs) are notoriously tough to take away from wastewater. Conventional water therapy programs don’t simply take away APIs from water, so pharmaceutical firms usually must resort to high-cost incineration as a substitute.

Consumer: World Pharmaceutical Firm

A well known pharma firm approached Arvia due to the precise situation above. The present disposal resolution was incineration however they wished to discover a higher resolution which was not as expensive, both financially or to the surroundings.

Downside: To cut back 4 APIs to PNEC ranges

The pharma big wanted to take away 4 APIs: ibrutinib, topiramate, rilpivirine (TMC278) and paliperidone palmitate. All 4 APIs needed to be diminished to under PNEC ranges (Predicted No-Impact Focus). No conventional water therapy programs had been in a position to do that, so the pharma firm had to take a look at new expertise.

Resolution

Arvia Know-how specialises in electrochemical oxidation for elimination of persistent natural compounds from industrial wastewater. The vary known as Nyex, and they’re all primarily based on a super-efficient electrochemical oxidation course of, both with or with out an integral adsorption course of in the identical unit.

For this challenge, Nyex Ellenox adopted by Nyex Rosalox diminished all 4 APIs to under PNEC values. To see how the Rosalox works, see this quick animation:

And for an outline of the merchandise see: https://arviatechnology.com/water-treatment-products/

End result

Nyex Ellenox and Nyes Rosalox together was proven to take away all 4 APIs to under the required ranges which meant the pharma firm might keep away from the prices of incineration

• Topiramate 1000μg/L
• Ibrutinib 1.55μg/L
• Ripilvirine 2.0μg/L
• Paliperidone palmitate 250 μg/L

Arvia’s CEO, Simon Gatcliffe stated, “Our consumer had budgeted for 1000 tonnes per 12 months to be incinerated, which equates to about 460,000 Euros. Our resolution represents a really robust ROI.”